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Research shows that CML cells with the BCR-ABL-T315I mutation treated with AKI603 display features typical of senescent cells, such as increased SA--Gal activity, altered morphology, elevated levels of p53, p21, p27, and p16, as well as SASP secretion [79]

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The good news is that most reactions are mild and short-lived: tenderness, a small bruise, or a bit of redness usually settle within 24 to 72 hours

[17] The film was produced by Gabriel Baca, David Gruban, and Andres Salazar [18] The creators of the movie also made a school curriculum to strengthen and highlight the morals within Baca's life story, containing a workbook and films